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FDA approves Emflaza to treat Duchenne muscular dystrophy

What is Emflaza?

Emflaza (Deflazacort) is a glucocorticoid, a class of corticosteroids used as an anti-inflammatory and immunosuppressant. Deflazacort works by decreasing inflammation and reducing the activity of the immune system to treat certain conditions such as: acute interstitial nephritis, anaphylaxis, asthma, anemia, Crohn’s disease, dermatomyositis, idiopathic thrombocytopenic purpura, juvenile chronic arthritis, acute and lymphatic leukemia, malignant lymphoma, rheumatoid arthritis, nephrotic syndrome, stemic lupus erythematosus, ulcerative colitis and many others.

What is Duchenne Muscular Dystrophy?

Duchenne muscular dystrophy is a rare genetic condition that weakens and deteriorates the muscles. The symptom of muscle weakness usually begins around 3 to 5 years, specially boys, affecting between 3,500 and 5,000 males at birth worldwide. Duchenne muscular dystrophy occurs due to an absence of dystrophin, a protein that protects muscle cells membranes. Two thirds of cases the patients inherited it from the parents, while one third of cases are due to a new mutation that affects the protein.

Emfalza (Deflazacort) works by improving muscle strength in patients with Duchenne muscular dystrophy, and it comes tablets and oral suspension.

Off-label indications or uses for Fluoxetine

An off-label indication or off-label drug use is when a doctor prescribes a medication for a treatment that still hasn’t been officially approved by the FDA (U.S. Food and Drug Administration). This means that a drug is being prescribed for a different use than the ones labeled to the FDA by the drug manufacturer.

In this blog post we’re going to write about the off-label uses for Fluoxetine, commonly known as Prozac, a drug that works affecting the communication between nerve cells in the Central Nervous System (CNS) and restoring the chemical balance in the brain. Fluoxetine is used for the treatment of some types of disorders, such as: depressive disorder, bulimia, obsessive-compulsive disorder (OCD) and panic disorder.

Off-label indications or uses for Fluoxetine

Fluoxetine antidepressant drug


Fibromyalgia: Fibromyalgia is a chronic musculoskeletal disorder characterized by widespread pain and tenderness and Fluoxetine helps decreasing the severity of pain.

Migraine: Fluoxetine can helps to reduce the severity of pain in patients with migraine who takes Fluoxetine for at least 3 months

Hot Flashes caused by hormonal chemotherapy: Fluoxetine helps to alleviate menopause symptoms such as hot flashes in a short term use

Raynaud’s phenomenon: Some studies shows that Fluoxetine reduces the attack frequency in patients with Raynaud’s phenomenon.

With MatchMyRx patients and providers can match medications with medical conditions to identify off-label indications or drug uses.

Off-label indications or uses for Propranolol

An off-label indication or off-label drug use is when a doctor prescribes a medication for a treatment that still hasn’t been officially approved by the FDA (U.S. Food and Drug Administration). This means that a drug is being prescribed for a different use than the ones labeled to the FDA by the drug manufacturer.

In this blog post we’re going to write about the off-label uses for Propranolol, this drug belongs to a group of drugs called beta-blocking agents and works by relaxing blood vessels to reduce blood pressure. Propranolol is used for the treatment of high blood pressure, chest pain (angina) and uneven heartbeat, also can be used to prevent migraine attacks.

Off-label indications or uses for Propranolol

Esophageal Variceal Bleeding: Esophageal Variceal Bleeding can be preventing with the use of beta blocking agents such as Propranolol because this drug can reduce the portal pressure and decrease the risk of bleeding from esophageal varices.

Panic disorder: Some physicians consider that beta blockers such as Propranolol can helps to reduce panic/anxiety attacks in patients with agoraphobia. But some studies reveals that Propranolol or other beta blockers has not enough impact in the treatment of those illness

Aggressive Behavior: Propranolol is used to manage aggression in some neuropsychiatric conditions such as schizophrenia and dementia.

With MatchMyRx patients and providers can match medications with medical conditions to identify off-label indications or drug uses.

Is Acetaminophen completely safe?

Is very probable that most of us, at least once, have taken Acetaminophen, commonly known as Tylenol, to treat headaches, minor pains, fever or for the common cold. However, have you ever thought about the risks of taking Acetaminophen?

Acetaminophen is considered a safe drug and that’s why we can even get it from vending machines at a public restroom. But, it’s important to be aware of which are the risks of abusing Acetaminophen before ending up at the ER. For example, let’s say you have the common flu, which means you have minor muscle pains, low fever, headache, runny nose and cough. You head out to you local pharmacy and buy Tylenol Extra Strength for the pain and Theraflu Daytime for the common cold symptoms. Both drugs recommend taking a dose every 6 hours (four times a day). What most people aren’t aware is that both of these medications contain Acetaminophen, which means your putting into your body 4.6 grams of the drug (2g from the Tylenol and 2.6g from the Theraflu), 600 milligrams above the daily dose recommended to avoid liver failure.

An over dosage of Acetaminophen (more than 4 grams daily) increases significantly the risk of liver failure. Acetaminophen, as all other drugs, is metabolized by the liver and then excreted through the urine. The excess Acetaminophen can’t be metabolized by the liver, which turns the excess into a toxin that can produce acute liver failure.

That’s why we must always consult a doctor before self-medicating an over-the-counter drug and always pay attention to the labels.

Medical Solutions

Private physician of remote GPs services in UK and Republic of Ireland, Medical Solutions, has recently enhanced its existing partnership with Alliance Health Group (AGG), with the introduction of ‘GP 24’, a full-featured 24-hour virtual GP service. Medical Solutions has partnered with AHG, in order to provide its existing GP service to employees in its private health plan population who are also covered by an independent private healthcare policy managed by AGG. These private health plans include both out-of-hours and in-office care, and are generally offered by independent healthcare agents. Since AGG is the largest private medical insurer in the United Kingdom, it is a natural fit for Medical Solutions, and the two companies have decided to strengthen their ties and work closely together going forward.

The’GP 24’portal

This portal is designed to streamline patient care across all medical solutions in the United Kingdom, Ireland and Europe. Through this portal, patients can request appointment with a clinician located in any location in the world at any time of day or night. The portal’s simple and easy-to-use interface allows doctors, clinicians and medical consultants to book appointments from anywhere in the world. They simply need to input a destination address and a time frame in which they wish to be contacted, and the system will contact them with a suitable response.

Furthermore, patients can also use the portal to make changes or cancel medical advice, depending on their needs. The new system will also allow patients to book appointments with more than one clinician in the event that they require multiple medical treatments. In addition, patients can schedule appointments with different doctors in different times zones if they so desire, or even submit a request to see a specific doctor in another part of the UK or Europe. This new system will greatly simplify medical advice requests by doctors, dramatically improving patient care.

However, there are other medical solutions that are being introduced into the healthcare sector that are creating huge changes for both healthcare professionals and patients. One such medical solution is the introduction of medical informatics. This is essentially computer-based techniques used to record medical information, as well as to conduct medical procedures and diagnose and treat patients more effectively. Medical informatics plays an important role in both the safety and quality of healthcare services across Europe and the rest of the world, and this type of medical software has already been successfully implemented in a number of hospitals in the United Kingdom.

Another medical solutions provider is a translation service that operates entirely through the internet. This company offers a number of online applications that can be accessed by medical practitioners across the world, allowing them to access highly specialized, specialist medical services wherever they are located. Such private fit notes applications include private fit notes management and medical transcription services. These services are particularly popular in countries like India and Pakistan where English is not a primary language. The companies that provide online translation services work closely with local healthcare providers in order to provide their clients with accurate translations of medical documents.

Private prescription delivery services are another popular medical solutions provider in a variety of countries across Europe. In the United Kingdom, one private prescription delivery company operates solely via the internet, allowing doctors and other medical professionals to receive, review, and manage their private prescriptions over the internet. In addition to private prescriptions, these types of medical solutions also offer generic and non-genetic prescription medication and prescription monitoring services. In a number of countries around the world, these companies will also provide consultations on a wide variety of healthcare issues, including healthcare education and advice.